
Acne can be a frustrating and persistent problem, affecting people of all ages. Luckily, there are several effective ingredients available to help control and treat acne. Understanding the best ingredients for treating acne can be the key to achieving clearer, healthier skin. This article discusses some of the top ingredients for treating acne: Mandelic acid, Benzoyl Peroxide, Niacinamide, Sulfur, Glycolic acid, and Hyaluronic acid.
Salicylic acid is a beta-hydroxy acid (BHA) that dives deep into pores, dissolving sebum, dead skin cells, and buildup that lead to breakouts. It’s one of the most proven ingredients for treating blackheads and whiteheads.
Bonus: it’s anti-inflammatory too, which helps reduce swelling and redness.
✅ Found in: Mixi Clean Gel Cleanser – a sulfate-free face wash that clears without stripping your skin.
If your breakouts are red, angry, and inflamed, benzoyl peroxide is your guy. It kills acne-causing bacteria and dries out active breakouts fast. Use it in moderation though,it can be drying and needs to be balanced with hydration.
✅ Found in: Mixi Clear Plex
An alpha hydroxy acid with larger molecules, mandelic acid exfoliates without the sting. It helps fade discoloration and unclog pores gently, perfect for sensitive or darker skin tones.
✅ Found in: Mixi Mandelic 8% Serum
Not all acne-fighting ingredients are drying. Hyaluronic acid is crucial to keep your skin hydrated while treating breakouts. It helps balance strong actives like retinoids or acids.
✅ Found in: Mixi Dew Drop Serum – keeps skin plump without clogging pores.
Glycolic acid is a more potent AHA that dissolves dead skin cells on the surface. It refines texture, fades scars, and enhances product absorption. Start slow, this one’s strong.
⚡ Great for: Post-acne marks, dullness, and rough patches.
Zinc PCA combines the oil-controlling benefits of zinc with the hydration support of PCA (a natural moisturizing factor). It reduces excess oil without over-drying, making it perfect for oily and acne-prone skin.
This multitasking ingredient reduces redness, regulates oil, and strengthens your skin barrier. It’s perfect for sensitive or reactive skin that still needs help with acne.
Bonus: it plays nicely with other ingredients.
Think of this as the underdog with quiet power. Azelaic acid unclogs pores, fights bacteria, and evens out skin tone—all without being too harsh. Great for hormonal acne, rosacea-prone skin, or deeper skin tones.
This age-old ingredient absorbs oil and dries out blemishes fast. It’s especially helpful for surface-level pimples and emergency spot treatment days.
⚡ Look for it in masks or overnight treatments.
When layering acne-fighting ingredients, use salicylic acid or benzoyl peroxide in the morning to clear pores and fight bacteria, while saving stronger exfoliants like retinoids, mandelic acid, or glycolic acid for nighttime when your skin is in repair mode. Always pair these actives with soothing ingredients like hyaluronic acid or niacinamide to keep your barrier calm and hydrated. Avoid combining glycolic acid and benzoyl peroxide at the same time unless professionally advised, as the combination can be overly harsh and lead to irritation or excessive dryness.
Using these ingredients in combination can often yield the best results in treating acne. For example, combining Benzoyl Peroxide with Niacinamide can help reduce irritation while treating acne. Similarly, using mandelic acid or glycolic acid alongside Hyaluronic acid ensures that the skin remains hydrated and less prone to irritation.
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